• br Discussion Metastatic RCC is

  2019-05-06

  

  Discussion Metastatic RCC is a fatal disease with survival often measured in months, rather than years. Surgery alone is the standard of care for patients who present with isolated renal disease at the time of diagnosis. However, approximately 1/3 of these patients will go on to develop clinicall

• To date over mutations in

  2019-05-06

  

  To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [

• Moving forward we identify several urgent

  2019-05-06

  

  Moving forward, we identify several urgent needs and challenges. First, the standing of p-Cresyl sulfate health workers in the health-care systems needs to be legitimised and moved away from largely grant-funded temporary employees or volunteers who might provide educational services towards skille

• br Introducci n Las encendidas palabras de fray Servando

  2019-05-06

  

  Introducción Las encendidas palabras de fray Servando Teresa de Mier provienen del Discurso preliminar que acompaña la reedición de la Brevíssima relación de la destruyción de las Indias de fray Bartolomé de las Casas, publicado en México en 1812. Fray Servando no duda en calificar al dominico, l

• Ante estas opiniones hay que tomar en cuenta que

  2019-05-06

  

  Ante estas opiniones, hay que tomar en cuenta que: “investigaciones recientes muestran que los pueblos indígenas han emergido junto norepinephrine bitartrate procesos de revitalización étnica y cultural, que han transformado el escenario sociopolítico y han puesto en tela de juicio las antiguas conc

• SGC707 This time last year to

  2019-05-06

  

  This time last year, to coincide with (March 9), launched a to highlight the rising burden of kidney disease and to encourage research partnerships to address gaps in knowledge and care, including the affordability of such care. Nephrology research and collaboration has come a relatively long way

• Bacterial LPS stimulates monocytes and tissue macrophages

  2019-05-06

  

  Bacterial LPS stimulates monocytes and tissue macrophages to release TNF-α and IL-1, which then stimulate secondary response cytokines, including IL-6. In addition to hematopoietic cells, IL-6 is synthesized by many different types of nonhematopoietic cells, including endothelium, lasting for an ext

• Leong et al reported a similar case

  2019-05-06

  

  Leong et al. reported a similar case of a short circuit in the Riata 1570 defibrillator lead, which manifested as unsuccessful defibrillation [10]. In this case, product analysis of generator indicated structural device damage owing to a short circuit in the defibrillation lead. Marenco et al. also

• 5z cost As Table shows all guidelines recommend OACs for pat

  2019-05-06

  

  As Table 2 shows, all guidelines recommend OACs for patients with a CHADS2 score of ≥2, whereas recommendations for low-risk patients with a CHADS2 score of 0/1 differ slightly across guidelines. Evidence indicating that novel OACs decrease the risk of ICH by half as compared with warfarin has affec

• The incidence of AF in Japan was

  2019-05-06

  

  The incidence of AF in Japan was also reported from an early cohort of the Hisayama Study [32] in the period between 1961 and 1984. Similar to the reports from Western countries, the incidence of AF increased with age in both men and women (Fig. 7) [32]. In a recent report of an observational cohort

• serine threonine protein kinase br Conflict of interest br A

  2019-05-06

  

  Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in

• En producto de un seminario organizado

  2019-05-05

  

  En 1971, producto de un seminario organizado por Norbert Lechner, Hinkelammert escribe un artículo titulado “La situación de la sexualidad dentro del materialismo histórico.” ¿Por qué, cellular metabolism definition pesar de sus contradicciones, el capitalismo “no explota en una crisis final”?, ¿cóm

• br The translational pipeline in biomedicine

  2019-05-05

  

  The translational pipeline in biomedicine (from bench to bedside) focused the attention of the global research all trans retinoic acid on delivery of results to patients. The notion was rapidly accepted, as shown by the training of researchers in translational approaches, the establishment of tra

• Immediate rollout of an effective and safe

  2019-05-05

  

  Immediate rollout of an effective and safe short-course treatment regimen is essential for the attack phase of the visceral leishmaniasis elimination programme, which aims to reduce the incidence to less than one case per 10 000 Bafilomycin A1 at risk. A single-dose liposomal amphotericin B regimen

• The region is also suffering from administrative negligence

  2019-05-05

  

  The region is also suffering from administrative negligence, extreme poverty, lack of basic health facilities, and weak infrastructure, which have increased its vulnerability to the climatic misery. Travel time to the nearest health facility is 2–4 h, at a cost of PKR 1000–4000 (US$10–40) in a regio

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