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br Ogolpe militar do dia de setembro de no
2019-06-06
Ogolpe militar do dia 11 de setembro de 1973, no Chile, destituiu do poder o então presidente Salvador Allende, eleito em 1970 pela Unidad Popular (up), coalizão política composta por partidos de esquerda que propunham purchase SB525334 “via chilena para o socialismo”. De acordo com Priscila Carlo
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br Methods br Results br Discussion Bisphosphonates reduce s
2019-06-05
Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve
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thip In summary we have established an animal model of human
2019-06-05
In summary, we have established an animal model of human NB bone metastasis in which COX-2/PGE2 plays a critical role. We provide pre-clinical data supporting the use of COX-2 inhibitors in the treatment of bone metastases in NB. Conflict of interest statement Introduction Desmoplastic fibrom
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Several anti platelet therapies have been evaluated in
2019-06-05
Several anti-platelet therapies have been evaluated in the context of bone metastasis. In vitro, a dual anti-platelet treatment using the soluble ADPase APT102 and an inhibitor of TxA2 synthesis (Aspirin) markedly affected tumor cell-induced platelet aggregation without altering tumor cell viability
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Se trata de una generaci n que creci a la
2019-06-05
Se trata de una generación que creció Kinase Inhibitor Library la sombra de un “experimento” como Poesía en movimiento, publicado por primera vez en 1966, pero que en 1990 había alcanzado la 21ª edición en Siglo XXI, antología que apostaba por la poesía de ruptura y el poema como signo (Escalante 20
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Una de las teor as m s destacadas
2019-06-05
Una de las teorías más destacadas sobre el género lo emparenta con el proyecto que llevaron Necrostatin 1 cabo autores alemanes como Bertold Brecht o Walter Benjamin, quienes: Ana María Amar Sánchez, teórica que propone esta línea genealógica para explicar la creación testimonial del argentino Rodo
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br Methods br Discussion We observed a significantly lower
2019-06-05
Methods Discussion We observed a significantly lower than expected Day +100 TRM. Other NMAT studies [4,5] have shown similar findings, although 60% of our trial retinoic acid receptor had high risk disease per the CIBMTR classification. In this and other studies, late TRM and disease progress
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br When many of us contemplate
2019-06-05
When many of us contemplate the role of agriculture in feeding 7·2 billion people, we picture large-scale, industrialised, and efficient systems that produce lots of food that is shipped around the world. Although those systems are relevant, they cotransporter are only one dimension of what agric
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br Introduction Percutaneous transcatheter device closure of
2019-06-05
Introduction Percutaneous transcatheter device closure of atrial septal defects (ASD) has become an effective alternative therapy to surgical repair in patients with secundum type ASD. Amplatzer ASD or ventricular septal defect (VSD) occluders were used for the closure of ASDs or VSDs, respective
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br Practical management of perioperative anticoagulation
2019-06-05
Practical management of perioperative anticoagulation and antiplatelet therapy in CIED surgery By integrating the current literature and the experience from our own practice, we developed a practical algorithm recently to guide the perioperative management of anticoagulation and antiplatelet ther
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Bepridil is a multichannel blocker suggesting that its pharm
2019-06-05
Bepridil is a multichannel blocker, suggesting that its pharmacological effects on cardiac myocytes are exerted by blocking Na [21], Ca [22], and K [23–25] channels. It has recently been reported that bepridil has a cardioprotective effect [26] by opening ATP-dependent K alzheimer\'s disease in mit
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Undoubtedly hydroxyurea has a huge potential for improving t
2019-06-01
Undoubtedly, hydroxyurea has a huge potential for improving the quality of lives of people affected by sickle-cell anaemia in settings where frequent and probably unsafe blood transfusions are the current standard of care. However, attention needs to be directed towards the potential adverse effects
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Si los sicarios y sus c rteles ejercen un oficio
2019-06-01
Si los sicarios y sus cárteles ejercen un oficio de tinieblas, donde “madrugar” es uno de los ejes rectores de un México violento, zafio, “kafkiano” y pulsante de impunidad, para Juan Villoro: Circunscrito por el crimen, la miseria y la muerte, el tema de una juventud cercada por la violencia es t
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years ago published a groundbreaking and taboo breaking Seri
2019-06-01
5 years ago, published a groundbreaking (and taboo-breaking) Series on stillbirths. Its powerful mix of advocacy and hard data attracted more media attention than perhaps any other Series, and made waves on numerous levels, from the individual to the intergovernmental. Working closely with countries
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br Methods br Results Four patients withdrew from the study
2019-06-01
Methods Results Four patients withdrew from the study due to elevated liver function, allergy to oxaliplatin, refusal of surgery, and refusal of chemotherapy, respectively. The total number of patients included in the final analysis was 31. The patients’ characteristics are presented in Table
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