• Our study found a significant association between the degree

  2020-06-03

  

  Our study found a significant association between the degree of primary tumor lobulation and EGFR mutations status (P Liproxstatin-1 status. However, only a small portion of these previous studies included the evaluation of lobulation, and almost all of them reported no association between EGFR mut

• Since the interaction between the E and E

  2020-06-03

  

  Since the interaction between the E2 and E3 is weak and transient, it has been difficult to identify novel interactions between specific E2/E3 complexes [59], [64]. Here we used a modified bait consisting of the Mulan RING domain fused to one of the four E2s isolated in our screen and expressed in y

• Enolase as a plasminogen receptor and activator

  2020-06-02

  

  Enolase, as a plasminogen receptor and activator localized on the surface of several helminths, can interact with the host fibrinolytic system (Yang et al., 2010, Du et al., 2009, de la Torre-Escudero et al., 2010). The enzyme is also one of excretory/secretory (ES) products in some helminths, such

• Although the reasons why viral RNA

  2020-06-02

  

  Although the reasons why viral RNA does not bind to and activate PKR in WNV-infected cells are not known, some of the known characteristics of flavivirus infections provide possible clues. The viral prostaglandin endoperoxide synthase protein forms dimers that associate with ER membranes and viral R

• The data regarding the association between COMT Val Met

  2020-06-02

  

  The data regarding the association between COMT Val158/108Met and cognitive function are divergent [10,11,12,22,24,25,26,27,28]. Better performance on the ROCF immediate and delayed recall test among veterans with PTSD who were Met carriers, compared to Val/Val homozygotes, agrees with findings show

• br Acknowledgements br Introduction Water and electrolytes c

  2020-06-02

  

  Acknowledgements Introduction Water and electrolytes constitute an integral part of all living things, and acetylcholine chloride governing their movements play important roles in a wide variety of physiological and/or pathophysiological processes. Given the importance of channel proteins in

• br Materials and methods br Results

  2020-06-02

  

  Materials and methods Results and discussion Conclusions Acknowledgments This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MEST) (No. 2011-0030635) and the MarineBio Research Program (NRF-C1ABA001-2011-0018561). The Fonta

• What would be the possible off target effects of

  2020-06-01

  

  What would be the possible off-target effects of enhancing Ndfip1 to control T cell responses? Increasing Ndfip1 activity could limit cytokine production in macrophages, where it has been shown to function in mouse BMDMs to degrade Tak1 and downregulate NFκB signaling [108]. Whether Ndfip1 regulates

• br Experimental section br Results

  2020-06-01

  

  Experimental section Results Discussion In our previous work (Rashidi et al., 2018) we isolated a novel glucarpidase whose raised DGAT-1 inhibitor did not cross-react with the one in clinical use. In principle, therefore, it would be possible to delay the production of antibodies in a pati

• The serotonin transporter gene encodes an integral membrane

  2020-06-01

  

  The serotonin transporter gene () encodes an integral membrane protein that transports serotonin from the synaptic spaces into the presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent way. This protein is a target of psychomotor stimulants

• br Casein Kinase II CK Casein Kinase II

  2020-06-01

  

  Casein Kinase II (CK2) Casein Kinase II (CK2) is a ubiquitous serine/threonine-selective pro-oncogenic protein kinase that has become a more prominent target for research due to its effects and key role in tumorigenesis (Gowda et al., 2017a, Pinna, 2002). CK2, a well-conserved, pleiotropic kinase

• br Acknowledgments br Casein kinases CK are serine

  2020-06-01

  

  Acknowledgments Casein kinases (CK) are serine/threonine-specific enzymes and can be divided two subtypes: casein kinase 1 (CK1) and casein kinase 2 (CK2). CK1 contains at least seven isoforms (α, β, γ1, γ2, γ3, δ and ε) expressed in eukaryotic organisms, CK1 is involved in various cellular pro

• It is common for plants that are deficient in P

  2020-06-01

  

  It is common for plants that are deficient in P to invest in their roots in order to maximise P uptake from the soil. Here, plants grown in soil amended with OA had a higher root biomass:shoot NSC228155 ratio compared with plants in the INORG-P treatment. Additionally, greater allocation of C to roo

• Estrogens Definition and history The term

  2020-06-01

  

  Estrogens: Definition and history The term “estrogens” refers to a group of female hormones, including estrone, estradiol, estriol, and estretrol (Fig. 1). Chemically, estrogens belong to the family of organic compounds known as steroids. As such, their core structure is composed of 17 carbon-carbo

• Flexible alignment of isopropylphenylaminobenzimidazole with

  2020-05-30

  

  Flexible alignment of 7-isopropylphenylaminobenzimidazole 16 with the lead Cy3 NHS ester 1 was performed using MOE. It was found that the aryl group of compound 16, exemplified as a yellow circle in Figure 2, overlapped well with the corresponding alkyl chain of compound 1 as well as the other key

14761 records 774/985 page Previous Next First page 上5页 771772773774775 下5页 Last page